> Around puberty the changing hormones, especially momentarily high estrogen in boys, can cause some obsessive episodes, and I suppose stress could be involved with early high [[testosterone]] production. A few small supplementations with [[thyroid]] or [[pregnenolone]] might reduce the stress and extend his growing years, but he could judge by whether it made him feel better. Lots of [[milk]] and [[fruit]] are appropriate in the teens, with [[eggs]], seafoods, and meats according to appetite. > [Cynoplus & Retin-A/Retinoids for Teenager] An eighth or tenth of a cynoplus tablet is a good amount for a trial, it's a little less than the body would normally produce in an hour, so it's enough to detect as a change of state, slight change of [[heart]] rate, warming of hands, for example. [[Vitamin A]] is such a basic metabolic factor, in the [[brain]] and endocrine glands, liver and kidneys, etc., I think it's dangerous to experiment with drugs that interfere with it. [(Reference)](https://archive.ph/o/OJZkW/https://raypeatforum.com/community/threads/ray-peat-email-advice-depository.1035/page-6%23post-27799)