> High estrogen does sometimes cause insatiable sexual interest, partly because it increases adrenal androgens, and partly by inhibiting satisfying orgasms. Too much [[progesterone]] can suppress or neutralize the androgens. [[thyroid]] is the best way to regulate the system, keeping libido up, making orgasms satisfying. > [Does masturbation or sex have positive or negative effects on the hormones or stress?] Generally positive, but intense arousal can have unwanted consequences, such as herpes virus outbreaks. > [Masturbation: effect on [[prolactin]]] I don't think masturbation affects the hormones more than regular sex does. [Forum Discussion](https://archive.ph/o/OJZkW/https://raypeatforum.com/community/threads/rp-email-advice-comment-effect-of-masturbation-on-[[[[prolactin]]]].13805/)