> The main way they [PUFA] are detoxified is by attaching glucuronic acid, making them water soluble, so they leave in the urine. Keeping the free fatty acids low in relation to albumin, they will largely be carried bound to the albumin to the liver. > They [polyunsaturated fats] are more water soluble, so are easier to release [from adipose tissue]. The fat cells themselves preferentially oxidize saturated fatty acids, so the stores tend to become more unsaturated with age.