> [[Hypothyroidism]] leads to increased estrogen and nitric oxide, and a decreased serum osmolarity (increased dilution of body fluids) and hyponatremia. [[Salt]], [[magnesium]], [[calcium]], [[aspirin]], antihistamine, [[progesterone]], tetracycline (or minocycline, doxycycline) and [[thyroid]] can correct the fluid imbalance. [(Reference)](https://archive.ph/o/OJZkW/https://raypeatforum.com/community/threads/ray-peat-email-advice-depository.1035/page-12%23post-141943)